MICROANATOMY

Detailed explanation-1: -Anaphase is the fourth step in mitosis. In anaphase, cohesin proteins binding the sister chromatids together break down.

Detailed explanation-2: -Metaphase. During metaphase, spindle fibers attach to the centromere of each pair of sister chromatids (see Figure below). The sister chromatids line up at the equator, or center, of the cell. This is also known as the metaphase plate.

Detailed explanation-3: -Explanation: Prophase is the first stage of mitosis, during which the cell begins to position itself in order to separate the chromatids and divide. During prophase, the nuclear envelope and nucleolus are dissolved and the chromosomes condense.