MICROANATOMY

Detailed explanation-1: -Metaphase leads to anaphase, during which each chromosome’s sister chromatids separate and move to opposite poles of the cell.

Detailed explanation-2: -Anaphase (from Ancient Greek -(ana-) ‘back, backward’, and (phásis) ‘appearance’) is the stage of mitosis after the process of metaphase, when replicated chromosomes are split and the newly-copied chromosomes (daughter chromatids) are moved to opposite poles of the cell.

Detailed explanation-3: -The segregation of the replicated chromosomes is brought about by a complex cytoskeletal machine with many moving parts-the mitotic spindle. It is constructed from microtubules and their associated proteins, which both pull the daughter chromosomes toward the poles of the spindle and move the poles apart.