MICROANATOMY

Detailed explanation-1: -Smooth ER is devoted almost exclusively to the manufacture of lipids and in some cases to the metabolism of them and associated products. In liver cells for example smooth ER enables glycogen that is stored as granules on the external surface of smooth ER to be broken down to glucose.

Detailed explanation-2: -Calcium Store The role of the smooth endoplasmic reticulum in calcium ion storage and release is of particular importance in the cells of the nervous and muscular system that use calcium-mediated signaling for excitation and contraction.

Detailed explanation-3: -The ER has been shown to be closely apposed to almost all membrane-bound organelles, including the PM, mitochondria, lipid droplets, Golgi, endosomes, and peroxisomes (Fig.