INTRODUCTION TO MICROSCOPY CELL BIOLOGY
ENDOPLASMIC RETICULUM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The defensive mechanism activated by the ER is called what?
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ER overuse
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ER stress response
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ER malfunction
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Common stress disorder
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Explanation:
Detailed explanation-1: -To cope with ER stress, mammalian cells activate a cytoprotective mechanism called the ER stress response (also called the unfolded protein response) [14, 15, 16, 17, 18].
Detailed explanation-2: -ER transmembrane receptors detect the onset of ER stress and initiate the unfolded protein response (UPR) to restore normal ER function. If the stress is prolonged, or the adaptive response fails, apoptotic cell death ensues.
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