MICROANATOMY

Detailed explanation-1: -These bones are called endochondral bones. In this process, the future bones are first formed as hyaline cartilage models. During the third month after conception, the perichondrium that surrounds the hyaline cartilage “models” becomes infiltrated with blood vessels and osteoblasts and changes into a periosteum.

Detailed explanation-2: -Endochondral Ossification This process involves the replacement of hyaline cartilage with bone. It begins when mesoderm-derived mesenchymal cells differentiate into chondrocytes. Chondrocytes proliferate rapidly and secrete an extracellular matrix to form the cartilage model for bone.

Detailed explanation-3: -Endochondral ossification is the process of bone development from hyaline cartilage. All of the bones of the body, except for the flat bones of the skull, mandible, and clavicles, are formed through endochondral ossification. In long bones, chondrocytes form a template of the hyaline cartilage diaphysis.

Detailed explanation-4: -Eventually, all the cartilage is replaced by bone. Thus, the cartilage tissue serves as a model for the bone that follows. The skeletal components of the vertebral column, the pelvis, and the limbs are first formed of cartilage and later become bone.

Detailed explanation-5: -[Membrane] bones develop from hyaline cartilage structures. False; Cartilage bones develop from hyaline cartilage structures. The organic bone matrix is called the [osteoid]. The enzyme alkaline phosphatase encourages the deposit of [collagen fibers] within the matrix of developing bone.