MICROANATOMY

Detailed explanation-1: -Bone is composed of various types of cells and collagenous extracellular organic matrix, which is predominantly type I collagen (85–95%) called osteoid that becomes mineralised by the deposition of calcium hydroxyapatite.

Detailed explanation-2: -In histology, osteoid is the unmineralized, organic portion of the bone matrix that forms prior to the maturation of bone tissue. Osteoblasts begin the process of forming bone tissue by secreting the osteoid as several specific proteins.

Detailed explanation-3: -Bone matrix (also known as osteoid) consists of about 33% organic matter (mostly Type I collagen) and 67% inorganic matter (calcium phosphate, mostly hydroxyapatite crystals).

Detailed explanation-4: -The osteoid matrix is calcified to form bone spicules. Osteoblasts trapped within the bone spicules either differentiate to osteocytes or undergo apoptosis. The bone spicules radiate outward from where the mesenchymal cluster originally formed.

Detailed explanation-5: -Osteoid is an unmineralized organic tissue that eventually undergoes calcification and is deposited as lamellae or layers in the bone matrix.