MICROANATOMY

Detailed explanation-1: -Hematopoiesis is blood cell production. Your body continually makes new blood cells to replace old ones. Hematopoiesis ensures you have a healthy supply of blood cells to supply oxygen to your tissue (red blood cells), fight infection (white blood cells) and clot your blood when you’re injured (platelets).

Detailed explanation-2: -In adults, hematopoiesis of red blood cells and platelets occurs primarily in the bone marrow. In infants and children, it may also continue in the spleen and liver.

Detailed explanation-3: -A number of studies have now confirmed that the development of the hematopoietic system, in humans and other mammals, occurs in two phases: a primitive hematopoietic phase that gives rise to transitory, bi-potent HSCs, and a definitive hematopoietic phase that generates long-lived, multipotent HSCs [3].