MICROANATOMY

Detailed explanation-1: -By definition, osteoid is the unmineralized, organic portion of the bone matrix that forms prior to the maturation of bone tissue. Osteoid refers to the young hyaline matrix of true bone in which calcium salts are deposited. Osteoid makes up about 50% the of bone volume and 40% of bone weight.

Detailed explanation-2: -Bone matrix (also known as osteoid) consists of about 33% organic matter (mostly Type I collagen) and 67% inorganic matter (calcium phosphate, mostly hydroxyapatite crystals). The osteoblasts occur as simple, epithelial-like layer at the developing bone surface.

Detailed explanation-3: -The organic matrix, called osteoid, is destined to undergo mineralization, a process starting when local Ca2 + and phosphate (PO43 −) ions reach levels high enough to precipitate, leading to the formation of hydroxyapatite crystals.

Detailed explanation-4: -Osteoid. Osteoideum. Synonyms: Preosseous matrix, Stratum preosseum. Osteoid, which translates to mean ‘like bone’ is defined as unmineralized bone tissue and is a key structure in the development of mature mineralized bone. Bone specific cells, known as osteoblasts secrete type I collagen and bone matrix proteins.

Detailed explanation-5: -Osteoid consists mostly of a fibrous protein called collagen, while the mineral complexes are made up of crystals of calcium and phosphate, known as hydroxyapatite, that are embedded in the osteoid. Bone also contains nutritive cells called osteocytes.