MICROANATOMY

Detailed explanation-1: -The plate is only found in children and adolescents; in adults, who have stopped growing, the plate is replaced by an epiphyseal line. This replacement is known as epiphyseal closure or growth plate fusion.

Detailed explanation-2: -The epiphyseal growth plate is the main site of longitudinal growth of the long bones. At this site, cartilage is formed by the proliferation and hypertrophy of cells and synthesis of the typical extracellular matrix. The formed cartilage is then calcified, degraded, and replaced by osseous tissue.

Detailed explanation-3: -Growth plates are located between the widened part of the shaft of the bone (metaphysis) and the end of the bone (epiphysis). The long bones of the body do not grow from the center outward. Instead, growth occurs at each end of the bone around the growth plate.

Detailed explanation-4: -Growth in height is driven by elongation of long bones due to chondrogenesis at the epiphyseal plates, also known as the growth plate.

Detailed explanation-5: -An epiphyseal line is an epiphyseal plate that has become ossified. The process of it forming from an epiphyseal plate is named epiphyseal closure. In adult humans, it marks the point of fusion between the epiphysis and the metaphysis.