MICROANATOMY

Detailed explanation-1: -The cells known as osteocytes are formed from metabolically inactive osteoblasts which have become entombed in a newly formed bone matrix during active bone formation. Osteocytes no longer secrete osteoid; however they do maintain their sensitivity to PTH and vitamin D and participate in calcium regulation.

Detailed explanation-2: -Inactive osteoblasts are called bone-lining cells; they have the potential of becoming active osteoblasts. The bone cells that are buried in the extracellular bone matrix are the osteocytes.

Detailed explanation-3: -These cells are described as osteocytes and remain in the bone matrix in a state of low metabolic activity. At the completion of a phase of bone formation, those osteoblasts which avoided entombment in lacunae lose their prominent synthetic function and become inactive osteoblasts, otherwise known as bone-lining cells.

Detailed explanation-4: -Osteocytes are inactive osteoblasts that have become trapped within the bone they have formed. Osteoclasts break down bone matrix through phagocytosis. Predictably, they are derived from the monocyte (macrophage) cell line. Think of osteoclasts as the “bone version” of the macrophage.