MICROANATOMY

Detailed explanation-1: -What are inotropes? Inotropic agents, or inotropes, are medicines that change the force of your heart’s contractions. There are 2 kinds of inotropes: positive inotropes and negative inotropes. Positive inotropes strengthen the force of the heartbeat. Negative inotropes weaken the force of the heartbeat.

Detailed explanation-2: -Inotropes are drugs that tell your heart muscles to beat or contract with more power or less power, depending on whether it’s a positive or negative inotrope. Positive inotropes can help when your heart can’t get enough blood to your body because it is too weak to pump the amount of blood your body needs.

Detailed explanation-3: -Inotropic drugs improve cardiac output and reduce pulmonary congestion in patients with left ventricular systolic dysfunction, but they must be used with caution because they increase myocardial oxygen consumption and add to myocyte calcium loading, both of which exacerbate myocardial ischemia.

Detailed explanation-4: -Inotropic – affects contractility. Chronotropic – affects heart rate (increase or decrease) Positive chronotropic drugs increase heart rate. Negative chronotropic drugs decrease the heart rate.