MICROANATOMY

Detailed explanation-1: -This process involves the replacement of hyaline cartilage with bone. It begins when mesoderm-derived mesenchymal cells differentiate into chondrocytes. Chondrocytes proliferate rapidly and secrete an extracellular matrix to form the cartilage model for bone.

Detailed explanation-2: -Endochondral ossification involves the replacement of hyaline cartilage with bony tissue. Most of the bones of the skeleton are formed in this manner. These bones are called endochondral bones. In this process, the future bones are first formed as hyaline cartilage models.

Detailed explanation-3: -Endochondral ossification is the mechanism responsible for the formation of all long bones of the axial skeleton (vertebrae and ribs) and the appendicular skeleton (limbs).

Detailed explanation-4: -Enchondral Ossification Examples include the femur, tibia, vertebrae, and metacarpals. The process begins in centers of ossification located in the embryonic skeleton and continues into the late teen years. Lengthening of the bone occurs in the epiphyseal growth plate.

Detailed explanation-5: -Intramembranous ossification is the process of bone development from fibrous membranes. Endochondral ossification is the process of bone development from hyaline cartilage. Long bones lengthen as chondrocytes divide and secrete hyaline cartilage. Osteoblasts replace cartilage with bone.