MICROANATOMY

Detailed explanation-1: -There are three types of cells that contribute to bone homeostasis. Osteoblasts are bone-forming cell, osteoclasts resorb or break down bone, and osteocytes are mature bone cells. An equilibrium between osteoblasts and osteoclasts maintains bone tissue .

Detailed explanation-2: -The osteoblasts occur as simple, epithelial-like layer at the developing bone surface. As the bone matrix mineralizes, some osteoblasts become trapped in small spaces within the matrix (lacunae). These trapped osteoblasts become osteocytes, the cells responsible for maintenance of the bony matrix.

Detailed explanation-3: -Each osteocyte is located in a space (lacuna) surrounded by bone tissue. Osteocytes maintain the mineral concentration of the matrix via the secretion of enzymes.

Detailed explanation-4: -Osteocytes, the cells residing within the bone matrix and comprising 90% to 95% of the all bone cells, have long been considered quiescent bystander cells compared to the osteoblasts and osteoclasts whose activities cause bone gain and loss, and whose dysfunction lead to growth defects and osteoporosis.

Detailed explanation-5: -Osteocytes are mature osteoblasts that have become trapped within the very bone matrix they produced. Osteocytes continue to form bone to some degree, which is important for maintaining the strength and health of the bone matrix.