MICROANATOMY

Detailed explanation-1: -Mesenchymal stem cells (MSCs) are multipotent cells capable of differentiating into osteoblasts, adipocytes, or chondrocytes, and have become the favorite source of cell-based therapy.

Detailed explanation-2: -Mesenchymal stem cells (MSCs) are multipotent stem cells that can differentiate into a variety of cell types, including bone cells (osteoblasts), cartilage cells (chondrocytes), muscle cells (myocytes) and fat cells that give rise to marrow adipose tissue (adipocytes).

Detailed explanation-3: -Osteoblasts originate from growth plate chondrocytes, bone marrow stromal cells, quiescent bone-lining cells, and other fibroblasts, such as suture fibroblasts or dental follicle cells.

Detailed explanation-4: -Osteoblasts and osteocytes originate from pluripotent mesenchymal stem cells. Mesenchymal stem cells commit to osteogenic lineage and differentiate into mature osteoblasts and osteocytes through osteoprogenitor cells and preosteoblasts in response to multiple stimuli.