MICROANATOMY

Detailed explanation-1: -The clinical features historically associated with PD are the triad of motor symptoms, namely, tremor, rigidity, and bradykinesia, with postural instability often appearing as the disease progresses.

Detailed explanation-2: -Bradykinesia. Bradykinesia refers to slowness of movement and is the most characteristic clinical feature of PD, although it may also be seen in other disorders, including depression.

Detailed explanation-3: -The presence of bradykinesia, rest tremor, rigidity and loss of postural reflexes are the most commonly identified motor symptoms of PD, although other clinical features can also be identified during disease progression, such as bulbar dysfunction, neuro-ophthalmological abnormalities and respiratory disturbances.

Detailed explanation-4: -Parkinson disease (PD) is a degenerative condition of the brain associated with motor symptoms (slow movement, tremor, rigidity and imbalance) and other complications including cognitive impairment, mental health disorders, sleep disorders and pain and sensory disturbances.