MICROANATOMY

Detailed explanation-1: -The myofilament contractile proteins consist of thick filament myosin and thin filament actin proteins. Bound to actin are a complex of regulatory proteins, which include tropomyosin and troponin-T, C, and I.

Detailed explanation-2: -Schematic depicting the basic structure of a contractile fiber, which consists of myosin containing contractile “thick” filaments, and actin “thin” filaments. Contractile bundles vary in thickness and have been shown to contain anywhere between 10 to 300 individual actin filaments [4].

Detailed explanation-3: -Myofilaments are the three protein filaments of myofibrils in muscle cells. The main proteins involved are myosin, actin, and titin. Myosin and actin are the contractile proteins and titin is an elastic protein.

Detailed explanation-4: -The contractile proteins are myosin, the principal component of thick myofilaments, and actin, which is the principal component of thin myofilaments.

Detailed explanation-5: -The sarcomere is the basic contractile unit for both striated and cardiac muscle and is made up of a complex mesh of thick filaments, thin filaments, and a giant protein titin.