MICROANATOMY

Detailed explanation-1: -The release of acetylcholine occurs when an action potential is relayed and reaches the axon terminus in which depolarization causes voltage-gated calcium channels to open and conduct an influx of calcium, which will allow the vesicles containing acetylcholine for release into the synaptic cleft.

Detailed explanation-2: -As a result of the action potential, the chemical transmitter acetylcholine (ACh) is released into the synaptic cleft. ACh diffuses across the synaptic cleft and binds to special receptors on the postsynaptic or the postjunctional membrane.

Detailed explanation-3: -ACh is the chief neurotransmitter of the parasympathetic nervous system, the part of the autonomic nervous system, that contracts smooth muscles, dilates blood vessels, increases bodily secretions, and slows heart rate. ACh can stimulate a response or block a response and thus can have excitatory or inhibitory effects.

Detailed explanation-4: -Cholinergic synapses are chemical synapses that use acetylcholine molecules as neurotransmitter. impulse reaches the synaptic knob of a presynaptic neuron.