MUSCLE NERVE CARTILAGE BONE
SKELETAL MUSCLE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Release energy through the breakdown of ATP
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Form cross-bridges with the active sites on actin molecules
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Produce tropomyosin to facilitate binding to actin molecules
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Bend and straighten during contraction due to the hinge attaching it to the rod portion
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Detailed explanation-1: -Myosins are the molecular motors best known for powering muscle contraction, but nonmuscle isoforms serve as intracellular cargo transporters, cytoskeletal anchors, and signaling molecules.
Detailed explanation-2: -Tropomyosins (Fig. Tropomyosins are contractile proteins which, together with the other proteins actin and myosin, function to regulate contraction in both muscle and non-muscle cells and are ubiquitous in animal cells.
Detailed explanation-3: -Myosin binding to actin induces conformational changes that are coupled to the nucleotide-binding pocket and amplified by a specialized region of the motor domain for efficient force generation. Tropomyosin plays a key role in regulating the productive interaction between myosins and actin.
Detailed explanation-4: -Tropomyosin blocks myosin binding sites on actin molecules, preventing cross-bridge formation and preventing contraction in a muscle without nervous input. Troponin binds to tropomyosin and helps to position it on the actin molecule; it also binds calcium ions.