MICROANATOMY

Detailed explanation-1: -Skeletal muscle can regenerate completely and spontaneously in response to minor injuries, such as strain. In contrast, after severe injuries, muscle healing is incomplete, often resulting in the formation of fibrotic tissue that impairs muscle function.

Detailed explanation-2: -Satellite cells can regenerate muscle fibers to a very limited extent, but they primarily help to repair damage in living cells. If a cell is damaged to a greater extent than can be repaired by satellite cells, the muscle fibers are replaced by scar tissue in a process called fibrosis.

Detailed explanation-3: -Skeletal muscle regeneration is an efficient stem cell-based repair system that ensures healthy musculature. For this repair system to function continuously throughout life, muscle stem cells must contribute to the process of myofiber repair as well as repopulation of the stem cell niche.

Detailed explanation-4: -Skeletal muscles have some ability to regenerate and form new muscle tissue, while cardiac muscle cells do not regenerate. However, new research suggests that cardiac stem cells may be coaxed into regenerating cardiac muscles with new medical strategies. Smooth muscle cells have the greatest ability to regenerate.