MICROANATOMY

Detailed explanation-1: -Skeletal muscle cells lack gap junctions for the simple reason that they do not need them. Skeletal muscles are not single cells. Rather, during replication, the cells don’t fully separate. This creates large, multinucleated cells that all share a continuous cytoplasm.

Detailed explanation-2: -The neuromuscular junction (NMJ) is a synaptic connection between the terminal end of a motor nerve and a muscle (skeletal/ smooth/ cardiac). It is the site for the transmission of action potential from nerve to the muscle.

Detailed explanation-3: -Skeletal muscle does not have any cell-cell junctions.

Detailed explanation-4: -Gap junctions occur in virtually all tissues of the body, with the exception of adult fully developed skeletal muscle and mobile cell types such as sperm or erythrocytes.