MICROANATOMY

Detailed explanation-1: -The increase in GnRH triggers a decrease in follicle-stimulating hormone and an increase in luteinizing hormone. These changes cause an ovary to release an egg (ovulation).

Detailed explanation-2: -Gonadotrophin-releasing hormone (GnRH) is released from the hypothalamus and binds to receptors in the anterior pituitary gland to stimulate both the synthesis and release of follicle stimulating hormone (FSH) and luteinising hormone (LH).

Detailed explanation-3: -The hypothalamus secretes GnRH in a pulsatile fashion, which triggers FSH and LH release from the anterior pituitary. These, in turn, act on the granulosa and theca cells in the ovary to stimulate follicle maturation and trigger ovulation.

Detailed explanation-4: -GnRH stimulates FSH release. The hypothalamus produces GnRH, and it is released into the hypophyseal portal circulation to act on G-protein-coupled receptors at gonadotropic cells of the anterior pituitary.