MICROANATOMY

Detailed explanation-1: -Spermatogonial stem cells (SSCs) are the germ stem cells of the seminiferous epithelium in the testis. Through the process of spermatogenesis, they produce sperm while concomitantly keeping their cellular pool constant through self-renewal.

Detailed explanation-2: -Sertoli cells are one of the most important cells necessary for sperm production in males. They are often identifiable as big, tightly linked cells near the basolateral portion of the seminiferous tubule. They are also known as sustentacular cells of Sertoli and are the nursemaid cells of the primary spermatogonia.[2]

Detailed explanation-3: -Spermatogenesis begins with spermatogonia (the diploid (2n) immature sperm cells derived from embryonic germ cells) dividing by mitosis. During their prolonged meiotic phase, the spermatocytes are sensitive to damage. Some of the spermatogonia develop into primary spermatocytes.