MICROANATOMY

Detailed explanation-1: -Leydig cells secrete testosterone in males. These are located in the interstitial compartment of the testis and nestled between the seminiferous tubules. They produce testosterone in response to luteinizing hormone (LH), which is produced and secreted by the pituitary gland.

Detailed explanation-2: -Leydig cells produce testosterone in the testes under the pulsatile control of pituitary luteinizing hormone (LH). cAMP is the intracellular messenger for LH action on steroidogenesis, and pharmacological evidence indicates that the response to LH can be modulated by cyclic nucleotide phosphodiesterases (PDEs).

Detailed explanation-3: -It is secreted by the interstitial cells of Leydig in the testes and by the adrenal glands in both males and females.

Detailed explanation-4: -Testosterone and other androgens are made by Leydig cells. The germ cells are fed by the Sertoli cells. They create a variety of proteins, including enzymes, hormones, androgen binding proteins, and inhibin. Sertoli cells do not produce testosterone.