MICROANATOMY

URINARY SYSTEM AND MALE FEMALE REPRODUCTIVE SYSTEMS

URINARY SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
____ are specialized epithelial cells of the distal convoluted tubule. These cells sense sodium chloride concentration in the tubule, which in turn reflects the systemic blood pressure.
A
Podocytes
B
Juxtaglomerular cells
C
Mesangial cells
D
Macula densa
Explanation: 

Detailed explanation-1: -The cells of the macula densa are sensitive to the concentration of sodium chloride in the distal convoluted tubule.

Detailed explanation-2: -The macula densa is a group of 15 to 20 cells that form the thickening on the surface of the distal convoluted tubule. This region is situated between the ascending limb of Henleā€™s loop and distal convoluted tubule. It is an area where the distal convoluted tubule is in direct contact with glomerulus.

Detailed explanation-3: -Macula densa cells in the distal nephron, according to the classic paradigm, are salt sensors that generate paracrine chemical signals in the juxtaglomerular apparatus to control vital kidney functions, including renal blood flow, glomerular filtration, and renin release.

There is 1 question to complete.