MICROANATOMY

Detailed explanation-1: -Very dark honey-or brown-colored urine could be a sign that you’re dehydrated and need to get more fluids. It may also be a warning sign of liver problems, so see your doctor if it doesn’t get better after a day or so.

Detailed explanation-2: -Medium-dark yellow urine is often an indication that you are dehydrated.

Detailed explanation-3: -When you have not drank enough fluids your kidneys try to save as much water as they can and cause your urine to be darker in colour (more concentrated). Dark yellow urine is a sign that you are dehydrated and that you must drink more fluids to prevent dehydration.

Detailed explanation-4: -During whole-body dehydration, urochrome concentration increases as antidiuresis is stimulated via increased arginine vasopressin production, thus increasing water reabsorption from the collecting duct of the nephron. This physiological response to dehydration results in darker and more concentrated urine (3, 4).