MUSCLE PHYSIOLOGY

PHYSIOLOGY

MUSCLE CONTRACTION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Power stroke will occur when
A
ATP binds to myosin head
B
Myosin head releases ADP and Pi
C
Myosin head hydrolyse ATP
D
Myosin binds to actin
Explanation: 

Detailed explanation-1: -The power stroke occurs when ADP and phosphate dissociate from the myosin head. The power stroke occurs when ADP and phosphate dissociate from the actin active site. The power stroke occurs when Ca2+ binds the calcium head.

Detailed explanation-2: -The myosin head moves toward the M line, pulling the actin along with it. As the actin is pulled, the filaments move approximately 10 nm toward the M line. This movement is called the power stroke, as it is the step at which force is produced.

Detailed explanation-3: -The “power stroke” mechanism for myosin movement along actin filaments: The direction in which the actin filament will be moved is dictated by the structural orientation of myosin in relation to the filament. A complete round of ATP hydrolysis produces a single ‘step’ or movement of myosin along the actin filament.

Detailed explanation-4: -(2) ATP then binds to myosin. (3) ATP is then hydrolyzed. (4) A cross-bridge forms and myosin binds to a new position on actin. (5) Pi is released and myosin changes conformation, resulting in the power stroke that causes the filaments to slide past each other.

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