MUSCLE PHYSIOLOGY

PHYSIOLOGY

MUSCLE ENERGETICS GLYCOLYSIS

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What process happens after glycolysis but before the citric acid cycle?
A
coenzyme A is broken off of pyruvate
B
a carbon atom is added to pyruvate to make a four carbon compound
C
glucose is split and produces two molecules of pyruvate
D
pyruvate is oxidized
Explanation: 

Detailed explanation-1: -In the presence of oxygen, the next stage after glycolysis is oxidative phosphorylation, which feeds pyruvate to the Krebs Cycle and feeds the hydrogen released from glycolysis to the electron transport chain to produce more ATP (up to 38 molecules of ATP are produced in this process).

Detailed explanation-2: -Figure 4.17 Pyruvate is converted into acetyl-CoA before entering the citric acid cycle.

Detailed explanation-3: -How pyruvate from glycolysis is converted to acetyl CoA so it can enter the citric acid cycle. Pyruvate is modified by removal of a carboxyl group followed by oxidation, and then attached to Coenzyme A.

Detailed explanation-4: -Pyruvate is the end product of a biochemical pathway called glycolysis, a series of reactions that converts one molecule of glucose into two molecules of pyruvate. Pyruvate then undergoes pyruvate oxidation to produce acetyl CoA, an intermediate in the Krebs cycle.

Detailed explanation-5: -In the presence of oxygen, pyruvate is transformed into an acetyl group attached to a carrier molecule of coenzyme A. The resulting acetyl CoA can enter several pathways, but most often, the acetyl group is delivered to the citric acid cycle for further catabolism.

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