MUSCLE PHYSIOLOGY

PHYSIOLOGY

MUSCLE ENERGETICS TCA CYCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
A single molecule of glucose generates ____ molecules of acetyl CoA, which enters the Krebs cycle.
A
1
B
2
C
3
D
4
Explanation: 

Detailed explanation-1: -A single molecule of glucose generates two molecules of acetyl CoA, which enters the Krebs cycle. Explanation: A single molecule of glucose generates two molecules of acetyl CoA, which enters the Krebs cycle. When glucose undergoes glycolysis Coenzyme A is acetylated to generate Acetyl-CoA.

Detailed explanation-2: -Two molecules of acetyl-CoA are produced from each glucose molecule so two turns of the Krebs cycle are required which yields four CO2, six NADH, two FADH2 and two ATPs.

Detailed explanation-3: -One glucose molecule breaks down into 2 pyruvic acids (3-carbon) in glycolysis, which is further decarboxylated to produce 2 acetyl CoA molecules, which enter the TCA cycle.

Detailed explanation-4: -Two molecules of carbon dioxide are given off.

Detailed explanation-5: -Krebs’ cycle produces 2 GTP(or 2ATP) through substrate level phosphorylation, Six molecules of NADH2 and 2molecules of FADH2 for every two molecules of Acetyl CoA oxidised by it.

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