MUSCLE PHYSIOLOGY

Detailed explanation-1: -With the stimulation of the presynaptic terminal, acetylcholine is released from the vesicles and into the synaptic cleft, where the neurotransmitter is free to bind with receptors.

Detailed explanation-2: -Acetylcholine is stored in vesicles at the ends of cholinergic (acetylcholine-producing) neurons. In the peripheral nervous system, when a nerve impulse arrives at the terminal of a motor neuron, acetylcholine is released into the neuromuscular junction.

Detailed explanation-3: -Acetylcholine is stored until the neurotransmitter needs to be released. After its synthesis, acetylcholine (ACh) is packaged into vesicles. ACh is transported from the cytoplasm into individual vesicles by means of a carrier protein on the vesicle membrane called the vesicular ACh transporter (VAChT).

Detailed explanation-4: -In the autonomic nervous system, acetylcholine (ACh) is the neurotransmitter in the preganglionic sympathetic and parasympathetic neurons.