PHYSIOLOGY
MYASTHENIA GRAVIS
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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It is believed that the IgG antibodies disrupt the chemical transmission of ACh at the neuromuscular junction by?
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Accelerating the breakdown of ACh
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Increasing WBC’s to septic levels
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Blocking the ACh from the receptor sites of the muscular cell
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Destroying the receptor sites
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Explanation:
Detailed explanation-1: -In myasthenia gravis, your immune system produces antibodies that block or destroy many of your muscles’ receptor sites for a neurotransmitter called acetylcholine (as-uh-teel-KOH-leen). With fewer receptor sites available, your muscles receive fewer nerve signals, resulting in weakness.
Detailed explanation-2: -Acquired myasthenia Gravis (MG), a disorder of impaired neuromuscular transmission is recognized as an autoimmune disorder, with a majority of the patients having antibodies against acetylcholine receptor (AChR antibodies) in the serum.
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