PHYSIOLOGY
MYASTHENIA GRAVIS
|
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
|
|
|
Disorders of the patient’s autonomic nerves
|
|
|
There is a counter impulse by the nerves to the brain and body
|
|
|
Impaired reception of ACH to ACH receptors on neurotransmitters
|
|
|
Disorders of muscle cells that inhibit ACH on neurotransmitters
|
|
|
Lack of muscle contraction during ACH reception at the synaptic junction
|
Detailed explanation-1: -In myasthenia gravis, your immune system produces antibodies that block or destroy many of your muscles’ receptor sites for a neurotransmitter called acetylcholine (as-uh-teel-KOH-leen). With fewer receptor sites available, your muscles receive fewer nerve signals, resulting in weakness.
Detailed explanation-2: -Myasthenia gravis (MG) is a relatively rare autoimmune disorder in which antibodies form against nicotinic acetylcholine (ACh) postsynaptic receptors at the neuromuscular junction (NMJ) of the skeletal muscles, causing muscle weakness and rapid muscle fatigue. It is a type-II hypersensitivity immune response.
Detailed explanation-3: -Myasthenia gravis is an autoimmune disease of the neuromuscular junction (NMJ) caused by antibodies that attack components of the postsynaptic membrane, impair neuromuscular transmission, and lead to weakness and fatigue of skeletal muscle.