PHYSIOLOGY
NEUROMUSCULAR JUNCTION TRANSMISSION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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ACh is released into the synaptic cleft.
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Calcium is pumped into the sarcolemma.
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Calcium is pumped into the motor neurons axon terminal.
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The muscle contracts.
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Detailed explanation-1: -An action potential (AP) arriving at the axon terminal membrane opens voltage-gated calcium channels in the membrane, which let calcium go in and initiate a membrane fusion reaction with synaptic vesicles, and release glutamate into the synaptic cleft.
Detailed explanation-2: –When the action potential reaches the axon ending, it causes vesicles to be released, their contents going into the synaptic gap. These chemicals are neurotransmitters.
Detailed explanation-3: -This stimulates voltage-gated calcium channels to open, allowing calcium ions to enter the motor neuron. This is described by statement (2). The influx of calcium ions into the motor neuron causes vesicles containing the neurotransmitter acetylcholine to fuse with the membrane of the motor neuron.