PHYSIOLOGY
NEUROMUSCULAR JUNCTION TRANSMISSION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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potassium ions
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calcium ions
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cross bridges
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acetylcholinesterase
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Detailed explanation-1: -Acetylcholinesterase (AChE) is a cholinergic enzyme primarily found at postsynaptic neuromuscular junctions, especially in muscles and nerves. It immediately breaks down or hydrolyzes acetylcholine (ACh), a naturally occurring neurotransmitter, into acetic acid and choline.
Detailed explanation-2: -However, in many regions of the body, acetylcholine is known to be the primary transmitter of the neuromuscular junction. Once acetylcholine is released by a cell, it is rapidly broken down in the extracellular space by the enzyme acetylcholine esterase to choline.
Detailed explanation-3: -An enzyme called acetylcholinesterase breaks down acetylcholine. Some drugs that are used to treat myasthenia gravis act on acetylcholinesterase to stop the breakdown of acetylcholine.