PHYSIOLOGY
SLIDING FILAMENT MODEL
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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True or false ____ Myosin detaches from actin when ATP binds to myosin
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True
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False
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Either A or B
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None of the above
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Explanation:
Detailed explanation-1: -After the power stroke, ADP is released; however, the cross-bridge formed is still in place, and actin and myosin are bound together. ATP can then attach to myosin, which allows the cross-bridge cycle to start again and further muscle contraction can occur (Figure 6.8).
Detailed explanation-2: -a. Myosin heads contain two functional sites, one for actin and one for tropomyosin–This option is incorrect because myosin heads have one for actin and one for ATP.
Detailed explanation-3: -ATP binds between two loops, the switch-1 loop and the P loop (so called for phosphate binding and conserved in nucleotide-binding proteins) at the heart of the myosin head.
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