NURSING ANM AND GNM

Detailed explanation-1: -Humalog is synthesised in a special non-disease-producing laboratory strain of Escherichia coli bacteria that has been genetically modified and is subsequently transformed and purified in a series of steps to yield zinc-insulin lispro crystals. These crystals are then formulated into the final drug product.

Detailed explanation-2: -The drug itself is synthesized by using a special non-pathogenic laboratory strain of the bacteria Escherichia coli which has been genetically altered by adding the gene for insulin lispro. Human insulin, normally secreted by the pancreas, has the amino acids lysine and proline at positions B28 and B29.

Detailed explanation-3: -Animal insulin was the first type of insulin to be administered to humans to control diabetes. Animal insulin is derived from cows and pigs. Until the 1980s, animal insulin was the only treatment for insulin dependent diabetes.