NURSING EXAM QUESTIONS
PHARMACOLOGY
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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The half-life of carboxyhemoglobin in a patient breathing 100% O2is
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5 minutes
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1 hour
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2 hours
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4 hours
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Explanation:
Detailed explanation-1: -Considering that the half-life of COHB is around 75 minutes on 100% oxygen at atmospheric pressure, 17 it is possible that the patient had a COHB level in the range of 45% when she was found in the car, assuming zero order kinetics.
Detailed explanation-2: -The elimination half life of CO after respiration of indoor air is about 320 minutes and can be reduced to 74 ± 25 minutes by treating patients with 100% oxygen (e47).
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