PATHOLOGY

Detailed explanation-1: -Hysteresis in the mammalian cell cycle control system In mammalian cells, cyclin E, in combination with a kinase subunit (Cdk2), sets off the programme of DNA synthesis, mitosis and cell division. The production of cyclin E is controlled by a transcription factor called E2F.

Detailed explanation-2: -Germ cells, or gametes, undergo meiosis, while somatic cells will undergo mitosis. After the cell proceeds successfully through the M phase, it may then undergo cell division through cytokinesis. The control of each checkpoint is controlled by cyclin and cyclin-dependent kinases.

Detailed explanation-3: -Cells regulate their division by communicating with each other using chemical signals from special proteins called cyclins. These signals act like switches to tell cells when to start dividing and later when to stop dividing.