PATHOLOGY

Detailed explanation-1: -Grade 3 Sprain (Severe) Significant tenderness and swelling around the ankle. May take 3-12 weeks or longer to recover. While some ankle sprains recover on their own, research has shown that patients may be less likely to have problems with long term ankle instability and re-injury if treated with physical therapy.

Detailed explanation-2: -Grade 1 sprain (mild): Slight stretching and some damage to the fibers of the ligament. Grade 2 sprain (moderate): Partial tearing of the ligament. There is abnormal looseness (laxity) in the joint when it is moved in certain ways. Grade 3 sprain (severe): Complete tear of the ligament.

Detailed explanation-3: -Ligaments heal through a distinct sequence of cellular events that occur through three consecutive phases: the acute inflammatory phase, the proliferative or regenerative phase, and the tissue remodeling phase.