PATHOLOGY MCQ
CELL DAMAGE
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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To prevent damaged cells before from dividing.
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To remove damaged cells from an organism.
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Either A or B
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None of the above
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Detailed explanation-1: -Cell cycle checkpoints are surveillance mechanisms that monitor the order, integrity, and fidelity of the major events of the cell cycle. These include growth to the appropriate cell size, the replication and integrity of the chromosomes, and their accurate segregation at mitosis.
Detailed explanation-2: -By delaying progression through the cell cycle, checkpoints provide more time for repair before the critical phases of DNA replication, when the genome is replicated, and of mitosis, when the genome is segregated.
Detailed explanation-3: -If the checkpoint mechanisms detect problems with the DNA, the cell cycle is halted, and the cell attempts to either complete DNA replication or repair the damaged DNA. If the damage is irreparable, the cell may undergo apoptosis, or programmed cell death 2.
Detailed explanation-4: -In the cell cycle, there are three major checkpoints-the G1 checkpoint, the G2 checkpoint, and the spindle checkpoint.
Detailed explanation-5: -The G2 Checkpoint If the checkpoint mechanisms detect problems with the DNA, the cell cycle is halted and the cell attempts to either complete DNA replication or repair the damaged DNA.