PATHOLOGY

Detailed explanation-1: -After DNA replication, each chromosome now consists of two physically attached sister chromatids. After chromosome condensation, the chromosomes condense to form compact structures (still made up of two chromatids). As a cell prepares to divide, it must make a copy of each of its chromosomes.

Detailed explanation-2: -When a single chromosome has been replicated in copies, each copy is called a sister chromatid. A special part of the chromosome called the centromere holds the two sister chromatids together.

Detailed explanation-3: -DNA replication during the synthesis (S) phase generates identical DNA molecules, which, in their chromatinized form, are called sister chromatids.

Detailed explanation-4: -A chromatid is one of the two identical halves of a chromosome that has been replicated in preparation for cell division. The two “sister” chromatids are joined at a constricted region of the chromosome called the centromere.