PATHOLOGY

Detailed explanation-1: -DNA is also susceptible to damage by environmental factors such as ultraviolet (UV), ionizing radiation, and alkylating agents used to treat proliferative disorders like cancer (Table 1).

Detailed explanation-2: -Environmental factors can also influence gene expression and cell differentiation. For example, available nutrients, salinity, and temperature are all factors that can influence gene expression in organisms.

Detailed explanation-3: -DNA is so important to cell differentiation because it has the instructions for all different types of specialization. Cell differentiation occurs due to differential gene expression, where some genes are turned on and others are turned off. Genes are coded for in the sequence of nucleotides present in the DNA.

Detailed explanation-4: -In the adult body, Hox genes are among others responsible for driving the differentiation of tissue stem cells towards their respective lineages in order to repair and maintain the correct function of tissues and organs.