PATHOLOGY

PATHOLOGY MCQ

CELL DAMAGE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which combination below is most likely to lead to the death of a potentially cancerous cell if there is a mutation in the cell’s proto-oncogene?
A
functioning telomerase gene, non-functioning stability gene, functioning tumor suppressor gene
B
non-functioning telomerase gene, non-functioning stability gene, non-functioning tumor suppressor gene
C
functioning telomerase gene, non-functioning stability gene, non-functioning tumor suppressor gene
D
functioning telomerase gene, functioning stability gene, functioning tumor suppressor gene
Explanation: 

Detailed explanation-1: -The most commonly mutated gene in people with cancer is p53 or TP53. More than 50% of cancers involve a missing or damaged p53 gene. Most p53 gene mutations are acquired. Germline p53 mutations are rare, but patients who carry them are at a higher risk of developing many different types of cancer.

Detailed explanation-2: -The more malignant the tumour is, the more apoptosis shows. In this study, we propose a new theory that apoptosis plays a key role in the malignant progression and metastasis of cancer.

Detailed explanation-3: -There are several types of lymphocytes, one of which is called a T cell. T cells are normally responsible for killing cancerous cells and cells infected by a virus, which is why they are used in CAR T-cell therapy.

Detailed explanation-4: -of errors that occur as cells divide. of damage to DNA caused by harmful substances in the environment, such as the chemicals in tobacco smoke and ultraviolet rays from the sun. (Our Cancer Causes and Prevention section has more information.) they were inherited from our parents. 11-Oct-2021

There is 1 question to complete.