PATHOLOGY

PATHOLOGY MCQ

CELL DAMAGE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What phase of mitosis do you get 2 new nuclei?
A
Prophase
B
Metaphase
C
Anaphase
D
Telophase
Explanation: 

Detailed explanation-1: -In anaphase, the shortest stage of mitosis, the sister chromatids break apart, and the chromosomes begin moving to opposite ends of the cell. By the end of anaphase, the 2 halves of the cell have an equivalent collection of chromosomes. In telophase, 2 daughter nuclei form. The nuclear envelope beings to reappear.

Detailed explanation-2: -Telophase is a phase of cell division where two new nuclear membranes form around the chromosomes to produce two distinct nuclei. Telophase occurs in both types of cell division in eukaryotes, mitosis and meiosis.

Detailed explanation-3: -During telophase, the newly separated chromosomes reach the mitotic spindle and a nuclear membrane forms around each set of chromosomes, thus creating two separate nuclei inside the same cell.

Detailed explanation-4: -Four haploid nuclei (containing chromosomes with single chromatids) are formed in telophase II.

Detailed explanation-5: -When prophase is complete, the cell enters prometaphase-the second stage of mitosis. During prometaphase, phosphorylation of nuclear lamins by M-CDK causes the nuclear membrane to break down into numerous small vesicles. As a result, the spindle microtubules now have direct access to the genetic material of the cell.

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