PATHOLOGY

PATHOLOGY MCQ

CELL DAMAGE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which best describes the role of p53 protein in the cell cycle
A
it makes sure organelles are properly replicated
B
it makes sure that the cytoplasm is equally divided
C
it make sure DNA is free of errors
D
It makes sure the DNA is copied
Explanation: 

Detailed explanation-1: -The TP53 gene provides instructions for making a protein called tumor protein p53 (or p53). This protein acts as a tumor suppressor, which means that it regulates cell division by keeping cells from growing and dividing (proliferating) too fast or in an uncontrolled way.

Detailed explanation-2: -p53 plays a prominent role as a facilitator of DNA repair by halting the cell cycle to allow time for the repair machineries to restore genome stability. In addition, p53 took on diverse roles to also directly impact the activity of various DNA-repair systems.

Detailed explanation-3: -A gene that makes a protein that is found inside the nucleus of cells and plays a key role in controlling cell division and cell death.

Detailed explanation-4: -Dubbed the ‘guardian of the genome’, p53 can kill mutated cells or prevent such cells from multiplying, which stops tumors from growing. However, if p53 itself becomes faulty, cells with damaged DNA can accumulate and potentially lead to cancer.

There is 1 question to complete.