PATHOLOGY

Detailed explanation-1: -Neutrophils are the most abundant leukocytes in the blood and they lead the first wave of host defense to infection or tissue damage.

Detailed explanation-2: -Neutrophils are not frequently observed in normal skin, but they are recruited in high numbers after tissue injury (Fig. 2). They are the first circulating inflammatory cell to move to the site of the wound, which is consistent with their primary role in defending against infection.

Detailed explanation-3: -Typically, neutrophils are the first responders to be recruited and have a higher microbicidal activity; whereas monocytes/macrophages are recruited later on.