PATHOLOGY

Detailed explanation-1: -Addison’s disease, also called adrenal insufficiency, is an uncommon illness that occurs when the body doesn’t make enough of certain hormones. In Addison’s disease, the adrenal glands make too little cortisol and, often, too little of another hormone, aldosterone.

Detailed explanation-2: -This is called an autoimmune disorder. Addison’s disease can develop if your immune system attacks your adrenal glands and severely damages your adrenal cortex. When 90% of the adrenal cortex is destroyed, your adrenal glands will not be able to produce enough of the steroid hormones cortisol and aldosterone.

Detailed explanation-3: -About Addison’s disease The adrenal glands are two small glands that sit on top of the kidneys. They produce essential hormones: cortisol, aldosterone and adrenaline. In Addison’s disease, the adrenal gland is damaged, and not enough cortisol and aldosterone are produced.