PATHOLOGY

Detailed explanation-1: -A pedigree shows relationships between family members and indicates which individuals have certain genetic pathogenic variants, traits, and diseases within a family as well as vital status.

Detailed explanation-2: -Pedigrees are used to analyze the pattern of inheritance of a particular trait throughout a family. Pedigrees show the presence or absence of a trait as it relates to the relationship among parents, offspring, and siblings.

Detailed explanation-3: -A pedigree chart displays a family tree, and shows the members of the family who are affected by a genetic trait.

Detailed explanation-4: -Pedigrees are normally used to represent simple dominant and recessive traits. For example, having a widow’s peak hairline is dominant. If an individual has that trait, their symbol on the pedigree will be shaded in.

Detailed explanation-5: -Males are represented as squares, while females are represented as circles. Shaded symbols mean an individual is affected by a condition, while an unshaded symbol means they are unaffected. A horizontal line between man and woman represents mating and resulting children are shown as offshoots to this line. More items