PATHOLOGY

Detailed explanation-1: -A female with one affected X chromosome is a “carrier” of hemophilia. Sometimes a female who is a carrier can have symptoms of hemophilia. In addition, she can pass the affected X chromosome with the clotting factor gene mutation on to her children. Learn more about the inheritance pattern for hemophilia.

Detailed explanation-2: -It almost always is inherited (passed down) from a parent to a child. Both hemophilia A and B are inherited in the same way, because both the genes for factor VIII and factor IX are located on the X chromosome (chromosomes are structures within the body’s cells that contain the genes).

Detailed explanation-3: -There are three types of genetic disorders: Single-gene disorders, where a mutation affects one gene. Sickle cell anemia is an example. Chromosomal disorders, where chromosomes (or parts of chromosomes) are missing or changed.

Detailed explanation-4: -The CBC is normal in people with hemophilia. However, if a person with hemophilia has unusually heavy bleeding or bleeds for a long time, the hemoglobin and the red blood cell count can be low.

Detailed explanation-5: -Answer: The Correct Answer is A blood clotting Disorder. Hemophilia is a clotting condition in which the blood does not clot properly. For blood to clot properly, a protein called clotting factor is required, and persons with haemophilia have little or no clotting factor.