PATHOLOGY

Detailed explanation-1: -Trisomy 21: About 95% of people with Down syndrome have Trisomy 21. With this type of Down syndrome, each cell in the body has 3 separate copies of chromosome 21 instead of the usual 2 copies.

Detailed explanation-2: -Trisomy 21, also known as Down syndrome, is a condition characterized by a distinctive pattern of minor and major anomalies associated with excess chromosome 21 material.

Detailed explanation-3: -Also known as Down syndrome, trisomy 21 is a genetic condition caused by an extra chromosome. Most babies inherit 23 chromosomes from each parent, for a total of 46 chromosomes. Babies with Down syndrome however, end up with three chromosomes at position 21, instead of the usual pair.

Detailed explanation-4: -Down syndrome (also known as trisomy 21) is an example of a condition caused by trisomy . People with Down syndrome typically have three copies of chromosome 21 in each cell, for a total of 47 chromosomes per cell. Monosomy, or the loss of one chromosome in cells, is another kind of aneuploidy.

Detailed explanation-5: -The classic form is the most common chromosomal disorder, in which there is one extra X chromosome resulting in the karyotype of 47, XXY [18]. Double aneuploidy was first described in a patient with both Down and Klinefelter (48, XXY, +21) syndromes. This is also the most commonly described double aneuploidy.