PATHOLOGY

PATHOLOGY MCQ

GENETICS AND DISEASE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
CRISPR can change DNA in humans and animals. What did scientists look at to help them create CRISPR?
A
Sheep cloning
B
Palindromic repeats
C
Common Cold
D
Bacteria fighting off viruses
Explanation: 

Detailed explanation-1: -CRISPR has been used to manipulate the genomes of organisms in humans and animals, among other living organisms. When it comes to drug discovery and development, CRISPR is used to remove or modify DNA in research mice to study disease phenotypes and develop new treatments.

Detailed explanation-2: -CRISPR/Cas9 edits genes by precisely cutting DNA and then letting natural DNA repair processes to take over. The system consists of two parts: the Cas9 enzyme and a guide RNA. Rapidly translating a revolutionary technology into transformative therapies.

Detailed explanation-3: -The breakthrough could provide a treatment for transthyretin amyloidosis, and even possibly reverse its effects. If transthyretin production levels are low enough, the body will begin to remove the protein more quickly than it’s created, Gillmore says.

Detailed explanation-4: -The CRISPR arrays allow the bacteria to “remember” the viruses (or closely related ones). If the viruses attack again, the bacteria produce RNA segments from the CRISPR arrays that recognize and attach to specific regions of the viruses’ DNA.

There is 1 question to complete.